Wednesday, March 19, 2008

March 19th

We apologize that we have not posted anything in weeks. The last several weeks have been chaotic and we have all been doing our best to get through each day with some energy left in the evening. We have some positive news to report. Robert completed his second round of chemo and felt well during the week of treatment and the week after. He was tired, but did not feel sick. This was a great relief as they had increased the dose for the second round and for the months ahead. He worked and did not even feel as fatigued as he had last month. He is working longer days this week to make up for the long appointment day that we will have on Mon 3/24. Robert will have another MRI and we will meet with our oncologist to review the results on the same day.

As always we are so thankful for the love and support that we receive from the people closest to us, the people that surround us, and from people that we have never even met. Your prayers and support help us to find peace.

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My Condition - Glioblastoma Multiforme (or GBM)

I was diagnosed with Glioblastoma Multiforme (GBM). This condition has four different grades (I - IV). My tumor is a grade IV GBM. This is the most aggressive GBM tumor. I have included a little section of The Essential Guide to BRAIN TUMORS below to describe the condition more completely.

Astrocytoma

An astrocytoma develops from star-shaped glial cells (astrocytes) that support nerve cells. These tumors can be located anywhere in the brain, but the most common location is in the frontal lobe. Astrocytomas are the most common primary CNS tumor.

The physician, usually the neurosurgeon or neurooncologist, will discuss the type and location of an astrocytoma. The pathologist will assign it a grade. Astrocytomas are generally classified as low or high grade. Low-grade astrocytomas (grades I and II) are slow growing. High-grade astrocytomas (grades III and IV) grow more quickly. The main tumor type is listed for each grade. There are additional tumor types in each of these grades.

The WHO classification divides astrocytomas into four grades:

  • Grade I Pilocytic Astrocytoma
  • Grade II Low-Grade Astrocytoma
  • Grade III Anaplastic Astrocytoma
  • Grade IV Glioblastoma Multiforme (or GBM)

Characteristics

The characteristics of an astrocytoma vary depending on the tumor’s grade and location. Most people are functioning normally when diagnosed with a low-grade astrocytoma. Symptoms tend to be subtle and may take one to two years to diagnose. This is because the brain can often adapt to a slow-growing tumor for a period of time. Highgrade tumors may present with changes that are sudden and dramatic.

Symptoms

  • Headaches
  • Seizures or convulsions
  • Difficulty thinking or speaking
  • Behavioral or cognitive changes (related to thinking, reasoning, and memory)
  • Weakness or paralysis in one part or one side of the body
  • Loss of balance
  • Vision changes
  • Nausea or vomiting